Manga Studio (known in Japan as ComicStudio) is a software application for Mac OS X and Microsoft Windows used for the digital creation of comics. It has been developed since 2001 by the Japanese graphics software company Celsys. It was originally distributed in the West by e frontier; since 2007 it is distributed by Smith Micro Graphics. There are two versions of the program: the full-featured Manga Studio EX, intended for professional artists (retail priced at US$299.99 as of 2010), and Manga Studio Debut, with a smaller feature set intended for amateurs and less advanced professional users (US$49.99).
credit to bagas31.com